Shiitake Mushroom (Lentinus edodes)<Back

Shiitake mushroom is a favored ingredient in Asian cooking. It not only enhances the flavor of food, but also carries long-cherished nutritional and medicinal benefits such as immune-boosting, antiviral and anticancer activities.


As a key ingredient included in our product Botano Guard™ and Immune Rebalancer, shiitake mushroom, the common Japanese name for Lentinus edodes, derives from the mushroom associated with the “shii” tree (Castanopsis cuspidate Schottky) and “take,” the Japanese word for mushroom. Because Japan is the world leader in production of this type of mushroom, the mushroom is now widely known by this name. These mushrooms are renowned in Far East countries (e.g., Japan, China, Korea, Thailand) as a food and medicine for thousands of years.

Traditional Uses of Shiitake Mushroom (Lentinus edodes)

  • Shiitake mushroom has a long history of use as a medicinal botanical. During the Ming Dynasty
    (AD1368–1644), physician Wu Juei wrote that the mushroom could be used not only as a food but as a
    medicinal mushroom, taken as a remedy for upper respiratory diseases, poor blood circulation, liver
    trouble, exhaustion and weakness, and to boost qi, or life energy.
  • It was also believed to prevent premature aging.

Modern Research - Shiitake Mushroom (Lentinus edodes)

  • Modern scientific studies at cellular, animal and clinical levels have confirmed various health benefits of
    shiitake mushrooms, such as strong immune boosting effects that help protect the body from a broad
    spectrum of acute infection, including acute influenza viral infection.

    WinVivo uses Shiitake Mushroom in products that address the following Health Concerns:

  • Travel Health and Safety
  • Compromised Immunity
  • Flu and Cold
  • Eczema

Articles about this botanical

Review of Cellular and Physiological Effects of Shiitake Mushroom and Reishi Mushroom

These mushrooms contain a large variety of biologically active polysaccharides with immunostimulatory properties, which contribute to their anticancer effects.

Review of Therapeutic Effects of Shiitake Mushroom and Reishi Mushroom

This review highlights some of the recently isolated and identified substances of higher Basidiomycetes mushrooms origin that express promising antitumor, immune modulating, cardiovascular and hypercholesterolemia, antiviral, antibacterial, and antiparasitic effects.

Immune-Stimulating and Anti-HIV Activities (Shiitake Mushroom)

Inhibition of the infectivity and cytopathic effect of human immunodeficiency virus by water-soluble lignin in an extract of the culture medium of Lentinus edodes mycelia (LEM).

Immune-Stimulating Activities (Shiitake Mushroom)

The water-soluble lignin in LEM (the extract of the solid culture medium of Lentinus edodes mycelia) has been known to have antiviral and immunopotentiating activities in vivo and in vitro.

Immune Response to Influenza Viral Infection (Shiitake Mushroom)

Low-dose supplementation with active hexose correlated compound improves the immune response to acute influenza infection in C57BL/6 mice.

Products containing this botanical

Botano Guard

Botano Guard™ capsules deliver a synergistic combination of natural immune boosters with broad-spectrum antiviral and antibacterial herbs that work together to build defensive and offensive protection against harmful microorganisms.


Immune Rebalancer

Immune Rebalancer capsules deliver a synergistic combination of botanicals that naturally regulate the immune system to de-sensitize your body to a broad spectrum of allergens.



Naturally Anti-Microbial
Naturally Anti-inflammatory
Desensitizes the Body to Allergens

Synergy for Faster Relief of Inflammation

Synergy for Faster Relief
of Lung Inflammation

Dissolves Mucus/Phlegm

Repairs Inflamed Throat

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