Anti-Inflammatory Effects of Ilex

Chem Biodivers. 2008 Jul;5(7):1369-76.
Two new triterpene saponins from the anti-inflammatory saponin fraction of Ilex pubescens root.
Wang JR, Zhou H, Jiang ZH, Liu L.

School of Chinese Medicine, Hong Kong Baptist University, 7 Baptist University Road, Kowloon Tong, Hong Kong.

 

The saponin fraction from the ethanolic extracts of the root of Ilex pubescens Hook. et Arn. (Ilexaceae) was found to exhibit potent anti-inflammatory effects on carrageenan-induced paw edema in rats. Two novel triterpene saponins, pubescenosides C and D (1 and 2, resp.), together with five known saponins were isolated from this saponin fraction. The structures of 1 and 2 were elucidated as (20beta)-3-O-[beta-D-glucopyranosyl-(1-->2)-beta-D-xylopyranosyl]ursa-12,18-dien-28-oic acid 28-O-beta-D-glucopyranosyl ester, and (20beta)-3-O-[alpha-L-rhamnopyranosyl-(1-->2)-beta-D-glucopyranosyl-(1-->2)-beta-D-xylopyranosyl]ursa- 12,18-dien-28-oic acid 28-O-beta-D-glucopyranosyl ester, respectively, on the basis of chemical and spectroscopic data. Five known saponins isolated from the saponin fraction were identified as ilexsaponin B(1), B(2), B(3), A(1), and chikusetsusaponin IV(a).

BOTANO GUARD:
Naturally Anti-Microbial
Anti-inflammatory

BOTANO GUARD + BOTANO THROAT:
Synergy for Faster Relief
of Lung Inflammation

BOTANO GUARD + IMMUNE REBALANCER:
Synergy for Faster Relief of Inflammation


BOTANO THROAT:
Dissolves Mucus/Phlegm

Repairs Inflamed Throat


IMMUNE REBALANCER:
Naturally Anti-inflammatory
Desensitizes the Body to Allergens


Natural, Potent Skin Treatment

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